Multimodal Pain Management

Multimodal pain management is a multidisciplinary approach to analgesia that targets both peripheral and central nerve transduction and various biochemical pathways, enzymes, and receptors that signal painful stimuli and inflammation

  • to utilize several medications to affect the pain pathway at multiple locations to minimize pain and minimize the overall narcotic consumption, and consequently minimize narcotic-related side effects.

Types

Patient-controlled analgesia

  • PCA pumps enable the patient to determine the dosing of intravenous fentanyl, morphine sulfate etc

Peripheral nerve blocks

  • THR – percutaneous insertion of a catheter intraoperatively at the site of the ipsilateral psoas muscle via a posterior approach in the lower lumbar region, targeting the lumbar plexus nerves

Local periarticular injections

  • morphine sulfate, NSAIDs like ketorolac, epinephrine, methylprednisolone, and local anesthetics such as bupivacaine or ropivacaine

Extended-release epidural morphine injection

  • DepoFoam technology, a biomedical technology that greatly increases the half-life of drugs in the body.
  • allows the pharmacokinetic agent to erode and rearrange into liposomal vesicles in the body compartment multiple times, thus keeping the medicine active for a greater period of time