Syndesmosis injury

Definition

  • Also referred to as a high ankle sprain
  • Involves one or more ligaments of the distal tibiofibular syndesmosis

Aetiology

  • Inversion trauma
  • External rotation injuries is the most common mechanism
  • Talus rotates laterally, widening the space between the tibia and fibula

Epidemiology

  • Difficult to have an exact incidence because it depends on the mode of diagnosis (clinical, versus radiological) used by the study.
  • Occurs in ~13% of ankle fractures
  • Occurs in ~6% of ankle sprains without fracture
  • Common in sports injuries

Anatomy

LateralMedial
Anterior talofibular ligament
Posterior talofibular ligament
Calcaneal fibular ligament
Lateral talocalcaneal ligament
Syndesmosis:
– Anterior inferior talofibular ligament – limits fibular external rotation
– Posterior inferior talofibular ligament – prevents posterior fibular translation
– Transverse talofibular ligament – limits posterior talar displacement
– Interosseous ligament – limits lateral translation of the fibular
Deltoid:
– Posterior tibiotalar
– Tibiocalcaneal
– Anterior tibiotalar
Calcaneonavicular (spring ligament)
Primary ligaments of the ankle

Classification systems

As per the European Society of Sports Traumatology, Knee Surgery and Arthroscopy-Ankle and Foot Associates consensus panel, the most common classification for syndesmotic injury is divided into acute, subacute and chronic.

Acute (<6 weeks):

  1. Stable – injured AITFL +/- IOL, intact deltoid ligament
  2. Unstable – depends on other injuries including:
    • Latent diastasis – injured AITFL, deltoid ligament +/- IOL
      • MRI diagnosis
    • Frank diastasis – injured all syndesmotic ligaments and deltoid ligament
      • XR diagnosis

Subacute (6 weeks – 6 months)

Chronic (>6 months)

History

  • Twisting like mechanism preceding the injury 
  • Anterolateral pain usually proximal to the AITFL
  • Limp on weight bearing
  • Medial tenderness + swelling 

Exam

  • Knee exam
  • Ankle and Foot exam
    • Pertinent findings: oedema not necessarily a feature (like it is for lateral sprains), antalgic heel raised gait, tenderness to palpation along AITFL
  • Pay attention to syndesmosis tenderness on palpation + check for Maisonneuve fracture
  • Special tests:
    • Hopkins squeeze test -> compression at mid tibia region causes pain. Good specificity
    • External rotation + dorsiflexion of foot with hip and knee at 90degrees causes pain at syndesmosis.
    • Cotton test (stronger predictive value) – moving talus side-to-side with a neutral ankle. Increased translation with associated pain is a positive test. This is more likely completed in theatre as it is unlikely to be tolerated whilst the patient is awake.
    • Fibular translation (stronger predictive value) Ã  increased translation of the fibula + pain elicited when anterior and posterior drawer force applied to the fibula. 

Investigations

  • XRays (44-58% specificity)
    • AP lateral and mortise views of ankle
      • Unilateral wt bearing of the mortise view is best, however may not be tolerated by pt. 
    • AP lateral of fibula – ?Maisonneuve fracture
    • Bilateral imaging
    • Interpretation:
      • Measure the distance between medial border of fibula and lateral posterior tibial prominence. This should be <6mm in anterior and mortise. If it’s more than this consider syndesmosis injury.
      • Measure the overlap distance between the medial border of the fibula and lateral border of the distal tibia, should be more than 6mm in AP and 1 mm in mortise. If less than these consider syndesmosis injury. 
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Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644422/
  • CT 
    • Normal Xrays, with ongoing clinical suspicion
    • Weight bearing CT scan – assesses degree of instability
  • MRI
    • Normal XRays with ongoing clinical suspicion. 
    • Confirms ligament injury
    • ~100% specificity

Differential diagnosis

  • Lateral ankle sprain
  • Maisonneuve fracture
  • Weber fractures

Treatment

  • Non-operative –> Rest, ice, elevate, NWB CAM boot or cast for 2-3 weeks, graded increase in physiotherapy exercises. Recovery time ~55 days
  • Operative
    • Indicated in syndesmotic sprain with instability (<6mm overlap b/w medial border of the fibula and lateral border of tibia, assoc fibula fracture)
    • Unsuccessful non-operative management  
    • Post operative – period of non weight bearing (2-6 weeks), followed by focused rehabilitation and return to sports usually by 12 weeks

Surgical technique

  • Screw fixation
Source: https://www.injuryjournal.com/article/S0020-1383(13)00444-0/fulltext
  • Suture button dynamic fixation
  • Ligament reconstruction

Complications

  • Post traumatic tibiofubular synostosis 
  • Degenerative ankle arthritis 

Prognosis

  • Favourable prognosis if identified and treated early
  • Can lead to instability

Quiz

Review your knowledge about ankle syndesmosis injury via this short quiz

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Created on By Deepti

Ankle syndesmosis injury quiz

A short quiz about ankle syndesmosis injury

1 / 5

Which of these mechanisms cause this type of injury? Multiple answers

2 / 5

What other conditions (differential diagnoses) can present in a similar manner? (multiple answers)

3 / 5

How long does it take, for healing in non-operative management?

4 / 5

When is surgical management indicated?

5 / 5

Which areas are affected by this type of injury? (multiple answers)

Your score is

The average score is 13%

0%

References

de-Las-Heras Romero J, Alvarez AML, Sanchez FM, et al. Management of syndesmotic injuries of the ankle. EFORT Open Rev. 2017;2(9):403-409. Published 2017 Sep 21. doi:10.1302/2058-5241.2.160084

Lin CF, Gross ML, Weinhold P. Ankle syndesmosis injuries: anatomy, biomechanics, mechanism of injury, and clinical guidelines for diagnosis and intervention. J Orthop Sports Phys Ther. 2006 Jun;36(6):372-84. doi: 10.2519/jospt.2006.2195. PMID: 16776487.

Schepers T, van der Linden H, va Lieshout EMM, Niesten DD, van der Elst M. Technical aspects of the syndesmotic screw and their effect on functional outcome following acute distal tibiofibular syndesmosis injury. Injury. 2014 Apr;45(4). doi: https://doi.org/10.1016/j.injury.2013.09.035

Shepherd D. Syndesmotic instability. Melbourne (AU): David Shepherd; 2022 [cited 5 Jan 2022]. Available from: https://drdavidshepherd.com.au/all-conditions/syndesmotic-instability/

Author Contributions

Francesca Sasanelli, created November 2021