FRACS Orthopaedic Exams
A fifty-three-year-old woman with a history of colitis, hypertension, and bipolar disorder presents to you with a two-year history of bilateral knee pain. Radiographs showed evidence of tricompartmental degenerative arthritis of both knees.
The patient underwent total knee arthroplasty of the right knee. During the procedure, the femoral canal could not be broached; the subchondral bone was dense and sclerotic. Bone cuts were unusually difficult because of the presence of sclerotic bone.
1. What is her diagnosis?
2. What is the pathophysiology behind this condition, and its heritance?