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- Infection
- Trauma
- Tumor include, leukemia, neuroblastoma etc
- Caffey’s disease
- Scurvy
- Hypervitaminosis A
Caffey Disease
- Infantile cortical hyperostosis
- Characteristics
- Febrile
- Hyperirratibility
- Swellin of the soft tissue
- Cortical thickening of bone
- Bones of jaw, forearm most affected
- Average onset is 9 weeks
- Rule out infection
- Usually expectant management
Hypervitiminosis A
- Xs leads to lysosomal rupture
Scurvy
- Defficiency of vit C
- Hydroxylation of proline & lysine requires Vit C as a cofactor
- Get abnormal physis & hemorhage below the periosteum
Tumoral Calcinosis
- Error of phosphate metabolism
- In skeletal mature patient – phosphate restriction, consider work up of hypervitaminosis D, hyperparathyroidism, collagen vascular disease
- Excision not always currative